On March 18, 2026, OPKO Health, Inc. announced the appointment of Subbarao V. Uppaluri, Ph.D. as a new director on its Board of Directors. Dr. Uppaluri's appointment comes in the wake of a vacancy created by the passing of Dr. Richard Krasno, who had served on the Board since February 2017. Dr. Uppaluri is expected to serve until the Company's 2026 Annual Meeting of Stockholders, and he is anticipated to join the Compensation Committee of the Board. The Board has confirmed that Dr. Uppaluri meets the independence criteria set forth by the Securities and Exchange Commission and the Nasdaq Stock Market.

Dr. Uppaluri brings a wealth of experience to the Board, having previously served as the Senior Vice President and Chief Financial Officer of OPKO Health from May 2007 until his retirement in July 2012. He continued to contribute to the company as a consultant until February 2014. His extensive background includes roles in strategic planning and financial management at IVAX and various senior positions in publicly traded banks. Dr. Uppaluri's diverse experience in finance and governance is expected to enhance the Board's effectiveness as OPKO navigates its strategic initiatives.

The appointment of Dr. Uppaluri is seen as a positive step for OPKO Health, as it strengthens the leadership team and brings additional expertise to the Board. The Company has not disclosed any arrangements or understandings regarding Dr. Uppaluri's selection, indicating a straightforward and independent appointment process. This move is likely to be well-received by investors, as it reflects the Company's commitment to maintaining strong governance practices and enhancing its operational capabilities.

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